Barrett’s Esophagus Cancer Symptoms

Neil Sharma MD

June 8, 2022

High-grade dysplasia and pain are three common symptoms of Barrett's sophist cancer

Neil Sharma MD pointed out that high-grade dysplasia and pain are three common symptoms of Barrett’s sophist cancer. The condition is caused by a genetic mutation known as amplification of a protein called PTEN. It is difficult to detect by symptom alone. GERD, also known as gastroesophageal reflux disease, may also be a sign of Barrett’s esophagus cancer.

High-grade dysplasia

Patients with Barrett’s esophagus may also experience high-grade dysplasia, which is a cellular process that indicates an elevated risk for cancer. Patients with dysplasia are typically monitored through periodic endoscopic biopsies. The recommended initial surveillance is twice a year or every three years, while those with Barrett’s need biannual follow-ups. Patients with high-grade dysplasia will require esophagectomy, which is the standard treatment for this disease. However, experimental procedures are being investigated as well.

The first step in diagnosing Barrett’s esophagus is an endoscopic examination. This examination will look for signs of dysplasia and may involve taking several mucosal biopsies. . These biopsies should be taken from the esophageal tissue on each side of the esophagus, and repeated every two centimeters or 3/4 inch proximally.


Neil Sharma MD disclosed that the condition of Barrett’s esophagus tissue occurs when it mutates into specialized columnar cells. This abnormal tissue is thought to be the final step before the esophagus develops into esophageal cancer. In fewer than one percent of people with the disorder, cancer will occur within the esophagus.

Treatment for Barrett’s esophagus begins with a diagnosis. The patient may be able to go home the same day or the next day. There are several options for treatment, which include surgical removal or dietary changes. One way to reduce the risk of developing Barrett’s esophagus cancer is to eat a diet high in fruits and vegetables. Additionally, losing weight may also lower your risk of developing the condition. There are different types of treatment for Barrett’s esophagus, including dietary changes, endoscopic ablative therapy, and pharmacological treatments.


One of the primary symptoms of Barrett’s oesophageal cancer is inflammation. Inflammation of the esophagus is common and can be a sign of this condition. There are many treatments available to treat this condition, including surgery and ablation with laser or radiofrequency energy. Inflammation can also occur as a side effect of some treatments, including those for Barrett’s.

A gastroenterologist will likely perform an upper endoscopy along with a biopsy to evaluate the lining of the esophagus for abnormalities. During an endoscopy, your healthcare provider will be able to view the lining of your esophagus using an endomicroscopy, which allows your doctor to view inside your body. During an endoscopy, a small sample of tissue will be removed and sent to a pathology lab for analysis.


Neil Sharma MD emphasized that while there is no known cure for Barrett’s esophagus, medications and surgery can control symptoms. Although treatment is not permanent, the early detection of Barrett’s esophagus can improve the chances of survival. Endoscopic mucosal resection, for example, can remove Barrett’s tissue through an endoscope. If Barrett’s esophagus is severe, endoscopic eradication therapy is an option.

If you notice that your GERD symptoms are worse than you’d like them to be, it’s time to see a doctor. In some cases, the underlying cause of Barrett’s esophagus is gastroesophageal reflux disease (GERD). GERD causes stomach acid to back up into the esophagus. In some cases.

Radiofrequency ablation

While RFA is an effective treatment for Barrett’s esophagus cancer, it also has some risks. Patients with long Barrett’s esophagus segments may have difficulty passing food due to bleeding and strictures, and lesions in the area of the hiatus hernia may pose an additional risk. Because of the risks, RFA for Barrett’s esophagus is recommended only when other treatment options have failed.

Neil Sharma MD remarked that a study published in the New England Journal of Medicine in 2008 found that RFA for Barrett’s esophagus did not eliminate the lesions, but it significantly reduced the risk of progression and cancer. However, more research is needed to determine the best candidates for the procedure. In the meantime.

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